This course is designed to enable students to apply the fundamental principles of engineering to bioengineering applications. It aims to provide a good understanding of biomechanics and biofluid dynamics. An understanding of biomechanics is important as mechanical forces are constantly experienced not only at the musculoskeletal but also the organ, tissue as well as cellular level. Mass transport is also vital for cell, tissue and organ functions; and 60% of body weight consists of body fluid. In this module, topics include biomechanics of the human musculoskeletal system and tissues, mechanics of biological structures at the nano/micrometer scale, rheology of biological fluids, mass transfer in tissue, and reactor analogy of cellular activity.